Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-[4-(p-Maleimidomethyl)Cyclohexane-Carboxamide] (Sodium Salt) is a high-purity, functionalized phospholipid derivative designed for advanced bioconjugation and drug delivery research. This compound is critical for creating stable, targeted liposomal and nanoparticle formulations by providing a reactive maleimide group for covalent attachment to thiol-containing ligands, such as antibodies, peptides, or targeting molecules. It is an essential building block for researchers and manufacturers in pharmaceutical development, diagnostic assay production, and advanced material science who require precise and reliable conjugation chemistry.

Application

• Targeted Drug Delivery Systems: Functionalization of liposomes and lipid nanoparticles (LNPs) for site-specific therapeutic delivery.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Conjugation of cytotoxic payloads to monoclonal antibodies via thiol-maleimide coupling.
• Diagnostic Probe Development: Labeling of proteins, peptides, or other biomolecules with fluorescent or radioactive tags for imaging and assays.
• Surface Modification of Nanomaterials: Creating biocompatible coatings on quantum dots, polymeric nanoparticles, or other carriers for in vivo applications.
• Biomimetic Membrane Research: Incorporation into model membranes to study cell surface interactions and signaling.
• Stable Ligand Immobilization: Covalent attachment of targeting moieties to lipid-based platforms for enhanced binding affinity and stability.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-[4-(p-Maleimidomethyl)Cyclohexane-Carboxamide] (Sodium Salt)
CAS No.	384832-87-5
Molecular Formula	C53H96N2NaO11P
Molecular Weight	991.3 g/mol
Synonyms	DPPE-MCC; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]; MCC-PE; Maleimide-Cap-DPPE; DPPE-PEG-Maleimide (related); 16:0 MCC PE; N-[(4-Maleimidomethyl)cyclohexanecarbonyl]-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine sodium salt; Functionalized Phospholipid 384832-87-5
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-[4-(p-Maleimidomethyl)Cyclohexane-Carboxamide] (Sodium Salt) is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and GMP-grade applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional integrity. We adhere to stringent in-process controls and final release testing protocols to meet the exacting standards of pharmaceutical development and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis. For long-term stability, store under an inert atmosphere (argon or nitrogen).

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Maleimide Functional Group Integrity	≥ 90%
Solubility	Soluble in chloroform, DMSO; forms micelles in aqueous buffer
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.