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Methyl 4-(((4-Amino-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)Benzoate CAS NO 384351-06-8


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CAS No.:384351-06-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 4-(((4-Amino-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)Benzoate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel kinase inhibitors and targeted therapeutics. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
  • Bioconjugation & Probe Development: Serves as a precursor for creating labeled compounds and biochemical probes for target identification and validation.
  • Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with specific biological activity.
  • Academic Research: Utilized in university and institutional labs for investigating new chemical reactions and biological pathways.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.

Basic Information

Product Name Methyl 4-(((4-Amino-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)Benzoate
CAS No. 384351-06-8
Molecular Formula C18H17N3O2S2
Molecular Weight 371.48 g/mol
Synonyms Methyl 4-({[(4-Amino-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]methyl})benzoate; 4-(((4-Amino-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)methyl)benzoic acid methyl ester; CAS 384351-06-8; Benzoic acid, 4-(((4-amino-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)methyl)-, methyl ester; Methyl p-(((4-amino-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)methyl)benzoate
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Quality Control

Our production of Methyl 4-(((4-Amino-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)Benzoate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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