Description

2-[(4-Fluorophenyl)Methyl]Hexahydro-1H-Azepine CAS NO 383130-08-3 is a fluorinated azepine derivative, a versatile nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is crucial for constructing complex pharmacophores and fine-tuning the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a structural component in the design of specialized ligands for catalysis and metal complexation.
• Material Science: Employed in the research of advanced polymers and functional materials requiring specific nitrogen-containing motifs.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Item	Details
Product Name	2-[(4-Fluorophenyl)Methyl]Hexahydro-1H-Azepine
CAS No.	383130-08-3
Molecular Formula	C13H18FN
Molecular Weight	207.29 g/mol
Synonyms	2-[(4-Fluorobenzyl)]Hexahydro-1H-Azepine; 2-(4-Fluorobenzyl)Hexahydro-1H-Azepine; 1H-Azepine, Hexahydro-2-[(4-Fluorophenyl)Methyl]-; 2-(4-Fluorobenzyl)Perhydroazepine; 4-Fluoro-α-(Hexahydro-1H-Azepin-2-yl)Methyl]Benzene; Azepine, Hexahydro-2-[(4-Fluorophenyl)Methyl]-; 383130-08-3
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorophenyl)Methyl]Hexahydro-1H-Azepine is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard is to supply material with a typical purity of ≥97% (by HPLC), with custom purity grades available upon request to meet specific research or GMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.