Description

2-(2-Fluorobenzyl)Pyrrolidine CAS NO 383127-84-2 is a high-purity fluorinated pyrrolidine derivative, a versatile and valuable building block in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical producers seeking to create next-generation compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probes: Useful for creating fluorinated molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-(2-Fluorobenzyl)Pyrrolidine
CAS No.	383127-84-2
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	2-[(2-Fluorophenyl)methyl]pyrrolidine; 1-(2-Fluorobenzyl)pyrrolidine; N-(2-Fluorobenzyl)pyrrolidine; Pyrrolidine, 2-(2-fluorobenzyl)-; 2-(2-Fluorobenzyl)azacyclopentane; α-(2-Fluorophenyl)-1-pyrrolidinemethane; 2-(2-Fluorophenylmethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorobenzyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong alkalis and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.