Description

(Z)-3-Benzyl-5-((7-Methyl-4-Oxo-2-(Piperidin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Methylene)-2-Thioxothiazolidin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers focused on developing new small-molecule drugs, especially in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Its structural features make it a candidate for the development of potential kinase inhibitors, targeting various disease pathways.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological processes and target identification.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high-complexity intermediates.
• Academic Research: Used in university and institutional labs for advanced organic synthesis methodology and heterocyclic chemistry studies.

Basic Information

Product Name	(Z)-3-Benzyl-5-((7-Methyl-4-Oxo-2-(Piperidin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Methylene)-2-Thioxothiazolidin-4-One
CAS No.	380889-71-4
Molecular Formula	C25H22N4O2S2
Molecular Weight	474.60 g/mol
Synonyms	3-Benzyl-5-[(7-methyl-4-oxo-2-piperidin-1-yl-4H-pyrido[1,2-a]pyrimidin-3-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one; (Z)-3-Benzylidene-5-((7-methyl-4-oxo-2-(piperidin-1-yl)-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)-2-thioxothiazolidin-4-one; 380889-71-4; Thiazolidinone derivative, CAS 380889-71-4; Pyrido[1,2-a]pyrimidine-thiazolidinone conjugate.
EINECS	Contact for details

Quality Control

Our production of (Z)-3-Benzyl-5-((7-Methyl-4-Oxo-2-(Piperidin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Methylene)-2-Thioxothiazolidin-4-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.