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2-{2-[4-Oxo-3-(1,3-Thiazol-2-Yl)-3,4-Dihydroquinazolin-2-Yl]Ethyl}-1H-Isoindole-1,3(2H)-Dione CAS NO 380646-79-7


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CAS No.:380646-79-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-{2-[4-Oxo-3-(1,3-Thiazol-2-Yl)-3,4-Dihydroquinazolin-2-Yl]Ethyl}-1H-Isoindole-1,3(2H)-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting specific enzymatic pathways.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new chemical entities.
  • Kinase Inhibitor Development: Its structural motifs suggest potential application in the research and development of kinase inhibitors, a major class of oncology and anti-inflammatory drugs.
  • Chemical Biology Probes: Can be utilized to create molecular probes for studying biological processes and target validation in cellular assays.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of specialized compounds for client projects.

Basic Information

Product Name 2-{2-[4-Oxo-3-(1,3-Thiazol-2-Yl)-3,4-Dihydroquinazolin-2-Yl]Ethyl}-1H-Isoindole-1,3(2H)-Dione
CAS No. 380646-79-7
Molecular Formula C21H14N4O3S
Molecular Weight 402.43 g/mol
Synonyms 2-(2-(4-Oxo-3-(thiazol-2-yl)-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione; 2-[2-[4-Oxo-3-(1,3-thiazol-2-yl)-3,4-dihydroquinazolin-2-yl]ethyl]-1H-isoindole-1,3(2H)-dione; 380646-79-7; Quinazolinone-thiazole-isoindoledione conjugate; Thiazolylquinazolinone ethyl phthalimide
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Quality Control

Our 2-{2-[4-Oxo-3-(1,3-Thiazol-2-Yl)-3,4-Dihydroquinazolin-2-Yl]Ethyl}-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance Off-white to light yellow powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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