Description

4-Fluoro-2-Isopropoxyaniline Hydrochloride is a high-purity, functionalized aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorine substituent with an isopropoxy group, making it an essential intermediate for creating complex, bioactive molecules. This compound is primarily needed by research and development teams, as well as process chemists, in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and alkoxy groups contribute to biological activity and metabolic stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material for the development of specialized electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for catalytic systems or as a scaffold for metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized fluorinated dyes and functional pigments.
• Academic and Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	4-Fluoro-2-Isopropoxyaniline Hydrochloride
CAS No.	380430-47-7
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	2-Amino-5-fluoroanisole hydrochloride; 4-Fluoro-2-isopropoxybenzenamine hydrochloride; 1-Fluoro-2-isopropoxy-4-aminobenzene hydrochloride; 2-Isopropoxy-4-fluoroaniline hydrochloride; Benzenamine, 4-fluoro-2-(1-methylethoxy)-, hydrochloride; 4-Fluoro-2-(propan-2-yloxy)aniline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Isopropoxyaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.