Description

3-(7-Methyl-4-Oxo-3,4,5,6,7,8-Hexahydro[1]Benzothieno[2,3-D]Pyrimidin-2-Yl)Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) with potential applications in various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential tool compound for investigating biological pathways and enzyme interactions due to its specific molecular architecture.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	3-(7-Methyl-4-Oxo-3,4,5,6,7,8-Hexahydro[1]Benzothieno[2,3-D]Pyrimidin-2-Yl)Propanoic Acid
CAS No.	380191-48-0
Molecular Formula	C15H16N2O3S
Molecular Weight	304.36 g/mol
Synonyms	3-[(7-Methyl-4-oxo-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-2-yl)]propanoic acid; 2-(2-Carboxyethyl)-7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-one; 380191-48-0; Propanoic acid, 3-(7-methyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)-; Tetrahydrobenzothienopyrimidinepropanoic acid derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Production can be aligned with current Good Manufacturing Practice (cGMP) principles for critical applications. Certificates of Analysis (COA) are provided with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. We maintain strict in-process controls and a fully documented quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.