Description

3-Amino-7-tert-Butyl-2-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and scale-up production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, especially in neurological and psychiatric drug research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in multi-step synthetic routes for target molecule production.
• Biochemical Research: Employed as a tool compound in biochemical assays and target validation studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry and organic synthesis methodology research.

Basic Information

Product Name	3-Amino-7-tert-Butyl-2-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	379250-29-0
Molecular Formula	C₁₇H₂₃N₃OS
Molecular Weight	317.45 g/mol
Synonyms	3-Amino-7-tert-butyl-2-methyl-5,6,7,8-tetrahydro-4H-[1]benzothieno[2,3-d]pyrimidin-4-one; 7-tert-Butyl-3-amino-2-methyl-4-oxo-4,5,6,7,8,9-hexahydro-1-benzothieno[2,3-d]pyrimidine; 379250-29-0; Benzothienopyrimidinone derivative; 4(3H)-Pyrimidinone, 3-amino-7-(1,1-dimethylethyl)-5,6,7,8-tetrahydro-2-methyl-[1]benzothieno[2,3-d]-; 3-Amino-7-tert-butyl-2-methyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 3-Amino-7-tert-Butyl-2-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against comprehensive specifications, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.