Description

n-(3,4-Dimethoxyphenethyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is essential for medicinal chemists and R&D departments in pharmaceutical and biotechnology companies seeking to develop new small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of potent and selective kinase inhibitors, a major class of oncology therapeutics.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening (HTS) and in vitro biochemical assays.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	n-(3,4-Dimethoxyphenethyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine
CAS No.	379245-32-6
Molecular Formula	C24H23N3O2S
Molecular Weight	417.52 g/mol
Synonyms	5-Phenyl-N-[2-(3,4-dimethoxyphenyl)ethyl]thieno[2,3-d]pyrimidin-4-amine; 379245-32-6; Thieno[2,3-d]pyrimidin-4-amine, 5-phenyl-N-[2-(3,4-dimethoxyphenyl)ethyl]-; N-(3,4-Dimethoxyphenethyl)-5-phenylthieno[2,3-d]pyrimidin-4-amine; 4-Amino-5-phenyl-N-(3,4-dimethoxyphenethyl)thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of our n-(3,4-Dimethoxyphenethyl)-5-Phenylthieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.