Description

Ethyl 5-[4-(Acetyloxy)Phenyl]-2-(3-Chlorobenzylidene)-7-Methyl-3-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the thiazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those with thiazolopyrimidine core structures.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in research laboratories.
• API Synthesis: Used in the pilot-scale and commercial-scale production of target active pharmaceutical ingredients for preclinical and clinical trials.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Production: Supplied to custom synthesis and contract manufacturing organizations (CMOs) for the production of specialized, high-value chemicals.

Basic Information

Product Name	Ethyl 5-[4-(Acetyloxy)Phenyl]-2-(3-Chlorobenzylidene)-7-Methyl-3-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate
CAS No.	378770-23-1
Molecular Formula	C25H21ClN2O5S
Molecular Weight	496.96 g/mol
Synonyms	Ethyl 5-(4-acetoxyphenyl)-2-[(3-chlorophenyl)methylene]-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate; 378770-23-1; Thiazolo[3,2-a]pyrimidine-6-carboxylic acid derivative; 5H-[1,3]Thiazolo[3,2-a]pyrimidine intermediate; 2-(3-Chlorobenzylidene)thiazolopyrimidine ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-[4-(Acetyloxy)Phenyl]-2-(3-Chlorobenzylidene)-7-Methyl-3-Oxo-2,3-Dihydro-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.