Description

Cyclopentanemethanamine, 1-(2-Fluorophenyl)- (9Ci) is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to construct complex molecular architectures for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorophenyl moiety for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up novel synthetic routes.

Basic Information

Product Name	Cyclopentanemethanamine, 1-(2-Fluorophenyl)- (9Ci)
CAS No.	378247-87-1
Molecular Formula	C12H16FN
Molecular Weight	193.26 g/mol
Synonyms	1-(2-Fluorophenyl)cyclopentanemethanamine; 1-(2-Fluorophenyl)cyclopentylmethanamine; (1-(2-Fluorophenyl)cyclopentyl)methanamine; α-(1-(2-Fluorophenyl)cyclopentyl)methylamine; 2-Fluoro-α-(aminomethyl)benzenepropanenitrile (related); Fluorophenyl cyclopentyl methylamine; (1-(2-Fluorophenyl)cyclopentyl)methylamine
EINECS	Contact for details

Quality Control

Our Cyclopentanemethanamine, 1-(2-Fluorophenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.