Description

2(1H)-Pyrimidinone,Tetrahydro-5-Hydroxy-1-(1-Methylethyl)-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate, enabling the construction of complex molecular architectures with high stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its specific stereochemistry can influence biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex natural product analogs and other high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in university and government laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	2(1H)-Pyrimidinone,Tetrahydro-5-Hydroxy-1-(1-Methylethyl)-(9Ci)
CAS No.	377093-12-4
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	5-Hydroxy-1-isopropyltetrahydropyrimidin-2(1H)-one; 1-Isopropyl-5-hydroxytetrahydro-2(1H)-pyrimidinone; Tetrahydro-5-hydroxy-1-(1-methylethyl)-2(1H)-pyrimidinone; 1-(Propan-2-yl)-5-hydroxypyrimidin-2-one; 377093-12-4; 5-Hydroxy-1-(1-methylethyl)tetrahydro-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for purity, enantiomeric excess, and related substances are available upon request. We adhere to cGMP principles for the manufacture of materials intended for research use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.