Description

Fmoc-Iminodipropionic Acid CAS NO 377087-65-5 is a specialized, high-purity amino acid derivative designed for advanced peptide synthesis and bioconjugation. This compound is a critical building block for introducing a unique, branched structure with a free carboxylic acid group, enabling precise control over molecular architecture in drug discovery and materials science. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex peptides, linkers, and functionalized biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected building block for introducing iminodipropionic acid moieties into peptide chains, creating branched structures or specific conformational constraints.
• Linker and Spacer Construction: Used in the design and synthesis of heterobifunctional cross-linkers, dendrimers, and PEGylation agents due to its two propionic acid arms and orthogonal protecting group.
• Drug Conjugation and Bioconjugation: Serves as a versatile intermediate for attaching drugs, dyes, or other functional molecules to peptides, proteins, or nanoparticles.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in medicinal chemistry.
• Advanced Material Synthesis: A precursor for functionalized polymers and smart hydrogels where precise amino acid-based functionality is required.
• Research & Development: A valuable tool for academic and industrial R&D focused on novel peptide mimetics, prodrugs, and bioorganic chemistry.

Basic Information

Product Name	Fmoc-Iminodipropionic Acid
CAS No.	377087-65-5
Molecular Formula	C21H21NO6
Molecular Weight	383.40 g/mol
Synonyms	N-Fmoc-iminodipropionic Acid; Fmoc-IDA; 9-Fluorenylmethyl N-(2-Carboxyethyl)-N-(2-carboxyethyl)carbamate; 3,3'-(Fmoc-imino)dipropionic Acid; (2,2'-((((9H-Fluoren-9-yl)methoxy)carbonyl)azanediyl)diacetic Acid; Fmoc-Dipropionic Acid; Fmoc-N-(2-Carboxyethyl)glycine; Fmoc-protected Iminodiacetic Acid Derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Iminodipropionic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.