Description

2-Chloro-5-(Pyridin-2-Yl)Pyrimidine is a versatile heterocyclic building block of significant importance in modern organic synthesis. This compound is valued for its dual-ring structure, which serves as a key pharmacophore and synthetic intermediate in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bioactive pyrimidine core.
• Ligand Synthesis: Serves as a key component for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Organic Electronic Materials: Investigated as a building block for electron-transport materials in OLEDs and other optoelectronic devices.

Basic Information

Product Name	2-Chloro-5-(Pyridin-2-Yl)Pyrimidine
CAS No.	374927-80-7
Molecular Formula	C9H6ClN3
Molecular Weight	191.62 g/mol
Synonyms	2-Chloro-5-(2-pyridinyl)pyrimidine; 5-(Pyridin-2-yl)pyrimidin-2-yl chloride; 2-Chloro-5-(2-pyridyl)pyrimidine; 2-(2-Chloropyrimidin-5-yl)pyridine; Pyrimidine, 2-chloro-5-(2-pyridinyl)-; 374927-80-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Pyridin-2-Yl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.