Description

(R)-1-(4-Fluorophenyl)Ethylamine is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates to ensure the efficacy and safety of their final products.

Application

• As a chiral resolving agent or auxiliary in asymmetric synthesis.
• Key chiral intermediate in the research and development of novel pharmaceutical compounds, particularly central nervous system (CNS) agents.
• Building block for the synthesis of advanced agrochemicals, such as herbicides and fungicides with specific stereochemical activity.
• Precursor for the preparation of chiral ligands used in catalysis (e.g., for asymmetric hydrogenation).
• Intermediate in the synthesis of liquid crystals and other advanced materials requiring specific optical properties.
• Starting material for academic and industrial research in medicinal chemistry and chemical biology.

Basic Information

Product Name	(R)-1-(4-Fluorophenyl)Ethylamine
CAS No.	374898-01-8
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	(R)-(+)-1-(4-Fluorophenyl)ethylamine; (R)-α-Methyl-4-fluorobenzylamine; (1R)-1-(4-Fluorophenyl)ethan-1-amine; (R)-4-Fluoro-α-methylbenzylamine; (R)-1-(4-Fluorophenyl)ethanamine; (R)-FPEA; (R)-FMEA; (R)-1-(4-Fluorophenyl)ethylamine hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Fluorophenyl)Ethylamine is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.