Description

4-(4-Chlorophenyl)-n-(2,3-Dimethylphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Serves as a structural motif in the development of new pesticides and herbicides, leveraging its tetrahydropyrimidine core.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and receptor-ligand interactions due to its specific pharmacophore.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for complex molecules.
• Custom Synthesis Building Block: Provided to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-(4-Chlorophenyl)-n-(2,3-Dimethylphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide
CAS No.	374600-77-8
Molecular Formula	C20H20ClN3OS
Molecular Weight	385.91 g/mol
Synonyms	4-(4-Chlorophenyl)-N-(2,3-dimethylphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; 4-(p-Chlorophenyl)-N-(2,3-dimethylphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; 374600-77-8; 5-Carboxamide, 4-(4-chlorophenyl)-N-(2,3-dimethylphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine; Tetrahydropyrimidine-5-carboxamide, 4-(4-chlorophenyl)-N-(2,3-dimethylphenyl)-6-methyl-2-thioxo-
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-n-(2,3-Dimethylphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.