Description

6-(Piperazin-1-Yl)-4-Chloropyrimidine is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a piperazine ring and a reactive chloropyrimidine core, makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Employed as a scaffold or linker molecule in the design of chemical probes and affinity purification tags.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Academic & Contract Research: Serves as a versatile reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	6-(Piperazin-1-Yl)-4-Chloropyrimidine
CAS No.	373356-50-4
Molecular Formula	C8H11ClN4
Molecular Weight	198.65 g/mol
Synonyms	4-Chloro-6-(piperazin-1-yl)pyrimidine; 4-Chloro-6-piperazin-1-ylpyrimidine; 6-(1-Piperazinyl)-4-chloropyrimidine; 4-Chloro-6-piperazinylpyrimidine; 373356-50-4; 6-Piperazin-1-yl-4-chloropyrimidine
EINECS	Contact for details

Quality Control

Every batch of 6-(Piperazin-1-Yl)-4-Chloropyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation, and impurity profile, is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.