Description

n-(2-Ethoxyphenyl)-4-(4-Fluorophenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide is a high-purity, complex heterocyclic compound serving as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring a tetrahydropyrimidine core with ethoxyphenyl and fluorophenyl substituents, makes it a valuable building block for medicinal chemistry research and development. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on synthesizing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for developing compounds with potential biological activity, particularly in central nervous system (CNS) or anti-inflammatory therapeutic areas.
• Process Chemistry Development: Serves as a reference standard or a critical intermediate during the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies due to its specific heterocyclic structure.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals for research purposes.

Basic Information

Product Name	n-(2-Ethoxyphenyl)-4-(4-Fluorophenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide
CAS No.	372971-52-3
Molecular Formula	C20H20FN3O2S
Molecular Weight	385.46 g/mol
Synonyms	4-(4-Fluorophenyl)-6-methyl-2-thioxo-N-(2-ethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide; 1,2,3,4-Tetrahydropyrimidine-5-carboxamide, 4-(4-fluorophenyl)-6-methyl-2-thioxo-N-(2-ethoxyphenyl)-; 372971-52-3; 4-(4-Fluorophenyl)-6-methyl-2-thioxo-N-(2-ethoxyphenyl)-3,4-dihydropyrimidine-5-carboxamide; 5-Carboxamide, n-(2-ethoxyphenyl)-4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine; Tetrahydropyrimidine Carboxamide Derivative
EINECS	Contact for details

Quality Control

Our n-(2-Ethoxyphenyl)-4-(4-Fluorophenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.