Description

6-Bromo-2,3,4-Trifluorobenzaldehyde is a versatile and highly functionalized aromatic aldehyde building block, distinguished by its unique combination of bromine and fluorine substituents. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a precursor for synthesizing complex heterocyclic and pharmaceutical intermediates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl or difluoromethyl ether groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and semiconductors, where the halogenated aromatic core influences electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create biaryl and other complex structures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	6-Bromo-2,3,4-Trifluorobenzaldehyde
CAS No.	372519-10-3
Molecular Formula	C7H2BrF3O
Molecular Weight	244.99 g/mol
Synonyms	2,3,4-Trifluoro-6-bromobenzaldehyde; 6-Bromo-2,3,4-trifluorobenzenecarboxaldehyde; Benzaldehyde, 6-bromo-2,3,4-trifluoro-; 2-Bromo-3,4,5-trifluorobenzaldehyde (isomer designation); 372519-10-3; Aldehyde, 6-bromo-2,3,4-trifluorobenzene-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3,4-Trifluorobenzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.