Description

Cyclopropanemethanamine, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci) is a high-value, chiral amine building block featuring a cyclopropane and a fluorinated aromatic ring system. This compound matters for its precise stereochemistry and structural complexity, which are critical for modulating the biological activity and pharmacokinetic properties of advanced pharmaceutical candidates. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the fluorophenyl and cyclopropane motifs can enhance activity and environmental stability.
• Ligand Synthesis: Acts as a precursor for chiral ligands and catalysts used in asymmetric synthesis to create other enantiomerically pure compounds.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore and optimize the pharmacophore of potential therapeutic molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanemethanamine, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	372184-03-7
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	(1R,2R)-2-(2-Fluorophenyl)cyclopropanemethanamine; rel-(1R,2R)-2-(2-Fluorophenyl)cyclopropanemethylamine; 2-(2-Fluorophenyl)cyclopropanemethanamine (rel-(1R,2R)-); (1R,2R)-2-(2-Fluorobenzyl)cyclopropanamine; 372184-03-7; (1R,2R)-2-(2-Fluorophenyl)cyclopropylmethylamine; (1R,2R)-rel-2-(2-Fluorophenyl)cyclopropanemethanamine
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanamine, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC to ensure high enantiomeric excess (ee) and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, chiral purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry inert atmosphere to preserve quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.