Description

Cyclopropanecarboxaldehyde, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci) is a high-purity chiral aldehyde building block, distinguished by its cyclopropane and fluorinated aromatic structure. This compound is critical for the synthesis of complex, biologically active molecules, offering precise stereochemical control and enabling the introduction of unique three-dimensional frameworks. It is primarily utilized by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the cyclopropane moiety enhances stability and bioactivity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new stereoselective synthetic methodologies.
• Material Science Precursor: Employed in the synthesis of specialized polymers and liquid crystals that require fluorinated aromatic components for specific electronic or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	372183-91-0
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	(1R,2R)-2-(2-Fluorophenyl)cyclopropanecarboxaldehyde; rel-(1R,2R)-2-(2-Fluorophenyl)cyclopropanecarbaldehyde; 2-(2-Fluorophenyl)cyclopropanecarboxaldehyde (rel-(1R,2R)-); (1R,2R)-rel-2-(2-Fluorophenyl)cyclopropanecarbaldehyde; 2-(o-Fluorophenyl)cyclopropanecarboxaldehyde, (1R,2R)-rel-; Cyclopropanecarboxaldehyde, 2-(2-fluorophenyl)-, (1R,2R)-rel-; (1R,2R)-2-(2-Fluorobenzyl)cyclopropanecarboxaldehyde (common misnomer); FCPCA (abbreviation)
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2-(2-Fluorophenyl)-, (1R,2R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.