Description

3-Nitro-4-(Trifluoromethyl)Benzyl Alcohol is a versatile aromatic building block characterized by its nitro and trifluoromethyl substituents. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials due to its electron-withdrawing nitro and CF3 groups, which influence charge transport properties.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments where the nitro group is integral to color development and lightfastness.
• Cross-Coupling Reactions: The benzyl alcohol moiety can be functionalized, making it a useful substrate in palladium-catalyzed cross-coupling reactions for creating complex biaryl structures.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers with tailored thermal and chemical resistance properties.

Basic Information

Product Name	3-Nitro-4-(Trifluoromethyl)Benzyl Alcohol
CAS No.	372119-86-3
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	4-(Trifluoromethyl)-3-nitrobenzyl alcohol; (3-Nitro-4-(trifluoromethyl)phenyl)methanol; 3-Nitro-α-(trifluoromethyl)benzenemethanol; 1-(Hydroxymethyl)-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-α,α,α-trifluoro-p-tolylcarbinol; Benzyl alcohol, 3-nitro-4-(trifluoromethyl)-; α-(Trifluoromethyl)-3-nitrobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.