Description

2-Aminomethylpyrimidine Hydrochloride is a versatile pyrimidine derivative salt, essential as a key building block in advanced organic synthesis. Its primary value lies in providing a functionalized pyrimidine scaffold with a reactive amine group, enabling the construction of complex heterocyclic molecules. This compound is particularly critical for pharmaceutical R&D and fine chemical manufacturing, where it serves as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides that require a functionalized pyrimidine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and material science applications.
• Fine Chemical Production: An intermediate in the manufacture of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-Aminomethylpyrimidine Hydrochloride
CAS No.	372118-67-7
Molecular Formula	C5H8N3Cl
Molecular Weight	145.59 g/mol
Synonyms	2-(Aminomethyl)pyrimidine Hydrochloride; Pyrimidine-2-methanamine Hydrochloride; 2-Pyrimidinemethanamine Hydrochloride; (Pyrimidin-2-yl)methanamine Hydrochloride; 2-Aminomethyl-pyrimidine HCl; 2-Pyridylmethanamine Hydrochloride (common misnomer); 2-(Aminomethyl)pyrimidine Monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminomethylpyrimidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.