Description

L-3-Thiobutyrine is a specialized sulfur-containing amino acid derivative with significant relevance in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block for the development of novel bioactive molecules and complex chemical architectures. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the synthesis of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Peptidomimetics Research: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Organocatalysis: Serves as a precursor or ligand in the development of novel asymmetric catalysts for stereoselective synthesis.
• Biochemical Probe Synthesis: Employed in the creation of labeled compounds and molecular probes for studying enzyme mechanisms and metabolic processes.
• Fine Chemical Synthesis: A valuable intermediate for constructing complex molecules in agrochemical and specialty material research.

Basic Information

Product Name	L-3-Thiobutyrine
CAS No.	371976-09-9
Molecular Formula	C4H9NO2S
Molecular Weight	135.18 g/mol
Synonyms	(2S)-2-Amino-4-sulfanylbutanoic acid; L-2-Amino-4-mercaptobutanoic acid; L-Homocysteine; L-3-Thiobutyrine; (S)-2-Amino-4-mercaptobutyric acid; L-4-Mercapto-2-aminobutyric acid; L-HomoCys-OH
EINECS	Contact for details

Quality Control

Our L-3-Thiobutyrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.