Description

6-Hydroxy-2-(3-Nitrophenyl)Quinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound matters as a critical building block for the research and development of novel therapeutic agents, particularly in oncology and kinase inhibitor programs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing potential drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted kinase inhibitors and other biologically active molecules.
• Organic Synthesis Building Block: Used in medicinal chemistry research for constructing complex quinazolinone-based scaffolds.
• Biochemical Research: Employed in academic and industrial laboratories to study enzyme inhibition and structure-activity relationships (SAR).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents.

Basic Information

Product Name	6-Hydroxy-2-(3-Nitrophenyl)Quinazolin-4(3H)-One
CAS No.	371946-32-6
Molecular Formula	C₁₄H₉N₃O₄
Molecular Weight	283.24 g/mol
Synonyms	6-Hydroxy-2-(3-nitrophenyl)-3,4-dihydroquinazolin-4-one; 2-(3-Nitrophenyl)-6-hydroxy-4(3H)-quinazolinone; 6-Hydroxy-2-(3-nitrophenyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 6-hydroxy-2-(3-nitrophenyl)-; 371946-32-6; 2-(3-Nitrophenyl)-6-hydroxyquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-2-(3-Nitrophenyl)Quinazolin-4(3H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.