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2-Imino-1-(2-Methoxyethyl)-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One CAS NO 371927-44-5


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CAS No.:371927-44-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Imino-1-(2-Methoxyethyl)-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors due to its dipyridopyrimidinone core structure.
  • Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological pathways and protein functions.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
  • Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name 2-Imino-1-(2-Methoxyethyl)-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One
CAS No. 371927-44-5
Molecular Formula C22H20N4O4S
Molecular Weight 436.49 g/mol
Synonyms 1,2-Dihydro-2-imino-1-(2-methoxyethyl)-3-[(4-methylphenyl)sulfonyl]-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one; 5H-Dipyrido[1,2-a:2',3'-d]pyrimidin-5-one, 1,2-dihydro-2-imino-1-(2-methoxyethyl)-3-[(4-methylphenyl)sulfonyl]-; 371927-44-5; 2-Imino-1-(2-methoxyethyl)-3-(p-tolylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one; 3-(4-Methylbenzenesulfonyl)-2-imino-1-(2-methoxyethyl)-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one
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Quality Control

Our 2-Imino-1-(2-Methoxyethyl)-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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