Description

1-(2-Hydroxyethyl)-2-Imino-10-Methyl-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing novel dipyridopyrimidinone-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Research: Serves as a reference standard or a probe molecule in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for advanced studies in heterocyclic chemistry and synthetic methodology development.

Basic Information

Item	Details
Product Name	1-(2-Hydroxyethyl)-2-Imino-10-Methyl-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One
CAS No.	370870-32-9
Molecular Formula	C22H22N4O4S
Molecular Weight	438.50 g/mol
Synonyms	1-(2-Hydroxyethyl)-2-imino-10-methyl-3-(p-tolylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one; 5H-Dipyrido[1,2-a:2',3'-d]pyrimidin-5-one, 1,2-dihydro-1-(2-hydroxyethyl)-2-imino-10-methyl-3-[(4-methylphenyl)sulfonyl]-; 370870-32-9; p-Toluenesulfonyl dipyridopyrimidinone derivative; Advanced dipyridopyrimidinone intermediate; Tolylsulfonyl-substituted pyrimidinone
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxyethyl)-2-Imino-10-Methyl-3-[(4-Methylphenyl)Sulfonyl]-1,2-Dihydro-5H-Dipyrido[1,2-A:2,3-D]Pyrimidin-5-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.