Description

1-m-Tolyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs targeting various disease pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for synthesizing potent and selective drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Research: Used as a reference standard and a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) with specific biological activity.
• Life Science Reagents: Employed in the creation of specialized biochemical tools and probes for cellular pathway analysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	1-m-Tolyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	370870-08-9
Molecular Formula	C12H11N5
Molecular Weight	225.25 g/mol
Synonyms	1-(3-Methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-(m-Tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 4-Amino-1-m-tolyl-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3-methylphenyl)-1H-; CAS 370870-08-9
EINECS	Contact for details

Quality Control

Our 1-m-Tolyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.