Description

β-Defensin-4 (Human) (Trifluoroacetate Salt) is a synthetic antimicrobial peptide corresponding to the human defensin-4 protein, provided as a trifluoroacetate salt for enhanced stability and solubility. This compound is a critical research tool for studying innate immune responses, epithelial defense mechanisms, and host-pathogen interactions. It is essential for researchers and developers in the fields of immunology, infectious disease, and pharmaceutical development, particularly for those investigating novel anti-infective and immunomodulatory therapies.

Application

• Immunological Research: Fundamental studies on the role of human defensins in innate immunity and inflammation.
• Antimicrobial Activity Studies: In vitro and ex vivo assays to evaluate efficacy against bacteria, fungi, and viruses.
• Drug Discovery & Development: Serving as a reference standard or lead compound for developing new peptide-based anti-infective agents.
• Cell Signaling & Pathway Analysis: Investigation of defensin-mediated cell signaling pathways and receptor interactions.
• Biomaterial & Wound Healing Applications: Research into incorporating antimicrobial peptides into coatings, dressings, or implants.
• Diagnostic Development: Potential use in developing assays to detect defensin levels as biomarkers for certain disease states.

Basic Information

Product Name	β-Defensin-4 (Human) (Trifluoroacetate Salt)
CAS No.	370570-43-7
Molecular Formula	C206H324N62O63S6 • xC2HF3O2
Molecular Weight	~4770 g/mol (Free peptide base)
Synonyms	Human β-Defensin 4; HBD-4; DEFB4; DEFB-4; BD-4; β-Defensin 4 Precursor; DEFB4A; DEFB104; hBD-4; Antimicrobial Peptide HBD-4; Trifluoroacetate salt of human β-defensin-4
EINECS	Contact for details

Quality Control

Our β-Defensin-4 (Human) (Trifluoroacetate Salt) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, peptide content, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Trifluoroacetate Content (HPLC)	≤ 10%
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.