Description

H-Gly-Trp-β-Na Hcl is a high-purity, protected dipeptide derivative used in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing therapeutic agents targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based drugs and bioactive compounds.
• Biochemical Research: Used in proteomics and enzymology studies to investigate peptide interactions and enzyme substrates.
• Neuropeptide Analog Development: Serves as a building block for creating analogs of tryptophan-containing neuropeptides.
• Combinatorial Chemistry: Employed in solid-phase and solution-phase peptide synthesis libraries for high-throughput screening.
• API Development: Utilized in the research and development stages of Active Pharmaceutical Ingredient (API) process chemistry.

Basic Information

Product Name	H-Gly-Trp-β-Na Hcl
CAS No.	370564-51-5
Molecular Formula	C₁₇H₂₁N₄O₄ • HCl
Molecular Weight	380.83 g/mol (Free base: 345.38 g/mol)
Synonyms	Glycyl-L-tryptophan benzyl ester hydrochloride; H-Gly-Trp-OBzl • HCl; Gly-Trp-OBzl hydrochloride; Benzyl glycyl-L-tryptophanate hydrochloride; N-(Benzyloxycarbonylglycyl)-L-tryptophan benzyl ester hydrochloride (related protected form); Z-Gly-Trp-OBzl hydrochloride (related protected form); Glycyl-L-tryptophan benzyl ester HCl; L-Tryptophan, glycyl-, benzyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our H-Gly-Trp-β-Na Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.