Description

3-(3-Pyridyl)-L-Alanine.Hcl CAS NO 369403-60-1 is a high-purity, non-proteinogenic amino acid derivative featuring a pyridyl side chain. This compound is a critical chiral building block in pharmaceutical research and development, particularly for the synthesis of novel drug candidates and bioactive molecules. It is essential for medicinal chemists and researchers in the pharmaceutical, biotechnology, and agrochemical industries who require high-quality, well-characterized intermediates for peptide synthesis and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and neurology.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique pyridylalanine residue, modifying peptide properties and interactions.
• Biochemical Research: Serves as a precursor or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Agrochemical Development: Employed in the synthesis of novel herbicides, pesticides, or plant growth regulators that utilize amino acid analogs.
• Ligand and Catalyst Design: Useful for creating novel chelating ligands or organocatalysts in asymmetric synthesis due to its chiral center and heterocyclic moiety.
• Diagnostic Reagent Development: Potential use in developing fluorescent probes or assay components for biochemical detection.

Basic Information

Product Name	3-(3-Pyridyl)-L-Alanine.Hcl
CAS No.	369403-60-1
Molecular Formula	C8H10N2O2·HCl
Molecular Weight	202.63 g/mol (Free base: 166.18)
Synonyms	L-3-(3-Pyridyl)alanine hydrochloride; (S)-2-Amino-3-(3-pyridyl)propionic acid hydrochloride; 3-(3-Pyridinyl)-L-alanine hydrochloride; β-(3-Pyridyl)-L-alanine HCl; 3-Pyridin-3-yl-L-alanine hydrochloride; H-3-Pal(3)-OH·HCl; (S)-3-(Pyridin-3-yl)alanine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Pyridyl)-L-Alanine.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.