Description

L-Tyrosine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3,5-Dimethyl- is a protected derivative of the amino acid L-Tyrosine, specifically engineered for peptide synthesis and advanced pharmaceutical research. This compound is critical for researchers and manufacturers requiring precise control over amino acid side-chain reactivity during solid-phase peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the controlled elongation of peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Biochemical Research: Employed in studies of protein structure, function, and protein-protein interactions.
• Combinatorial Chemistry: A valuable reagent for generating diverse peptide libraries for screening and discovery.
• Protecting Group Chemistry: Demonstrates the application of the Fmoc (9-fluorenylmethoxycarbonyl) protecting group for amine functionality.

Basic Information

Product Name	L-Tyrosine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3,5-Dimethyl-
CAS No.	369401-19-4
Molecular Formula	C28H27NO5
Molecular Weight	457.52 g/mol
Synonyms	Fmoc-3,5-Dimethyl-L-tyrosine; Fmoc-Tyr(3,5-Me)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,5-dimethyl-L-tyrosine; Fmoc-3,5-diMeTyr-OH; Fmoc-Dmt-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-(3,5-dimethyl-4-hydroxyphenyl)propanoic acid; Fmoc-L-Tyr(3,5-diMe)-OH; Protected L-Tyrosine derivative
EINECS	Contact for details

Quality Control

Our L-Tyrosine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3,5-Dimethyl- is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.