Description

4,6(1H,5H)-Pyrimidinedione, 1-(2,3-Dichlorophenyl)-5-[[5-(Diethylamino)-2-Furanyl]Methylene]Dihydro-2-Thioxo- is a high-value, structurally complex heterocyclic compound featuring a pyrimidinedione core with a thioxo group and a diethylamino-substituted furan moiety. This compound is significant for its role as a key synthetic intermediate in advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents and high-performance chemical products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, or enzyme inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or plant growth regulators, leveraging its unique heterocyclic structure for biological activity.
• Organic Synthesis & Material Science: Acts as a precursor for complex organic molecules with potential applications in advanced materials, such as organic semiconductors or ligands for catalysis.
• Biochemical Research: May be utilized as a tool compound or a scaffold in biochemical assays to study protein-ligand interactions or enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	4,6(1H,5H)-Pyrimidinedione, 1-(2,3-Dichlorophenyl)-5-[[5-(Diethylamino)-2-Furanyl]Methylene]Dihydro-2-Thioxo-
CAS No.	366830-18-4
Molecular Formula	C19H17Cl2N3O2S
Molecular Weight	422.33 g/mol
Synonyms	1-(2,3-Dichlorophenyl)-5-[(5-(diethylamino)furan-2-yl)methylene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 1-(2,3-Dichlorophenyl)-5-[[5-(diethylamino)-2-furanyl]methylene]-2-thioxo-4,6(1H,5H)-pyrimidinedione; 2-Thioxo-1-(2,3-dichlorophenyl)-5-[(5-(diethylamino)furan-2-yl)methylene]pyrimidine-4,6(1H,5H)-dione; CAS 366830-18-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical and agrochemical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.