Description

Rivaroxaban CAS NO 366789-02-8 is a highly potent and selective direct Factor Xa inhibitor, representing a significant advancement in anticoagulant therapy. This active pharmaceutical ingredient (API) is critical for the development and production of next-generation oral anticoagulant medications. It is primarily required by pharmaceutical manufacturers and research institutions focused on cardiovascular disease, thrombosis prevention, and innovative drug delivery systems.

Application

• Pharmaceutical API: Core active ingredient in the formulation of oral anticoagulant tablets (e.g., Xarelto®).
• Clinical Research: Used in preclinical and clinical studies for investigating new indications and dosage forms.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of rivaroxaban-based medications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in laboratories.
• Drug Discovery: A key compound for structure-activity relationship (SAR) studies in the design of novel Factor Xa inhibitors.
• Formulation Development: Utilized in R&D for developing improved solid dosage forms with enhanced bioavailability.

Basic Information

Product Name	Rivaroxaban
CAS No.	366789-02-8
Molecular Formula	C19H18ClN3O5S
Molecular Weight	435.88 g/mol
Synonyms	BAY 59-7939; Xarelto; 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide; Rivaroxabanum; UNII-9NDF7JZ4M3
EINECS	Contact for details

Quality Control

Our Rivaroxaban is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) that comply with current pharmacopeial standards (USP/EP) and ICH guidelines to support regulatory filings for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.15%, Total impurities ≤ 0.5%
Water (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.