Description

1H-Isoindol-1-One,4-Fluoro-2,3-Dihydro-(9Ci) is a specialized fluorinated isoindolinone derivative, a high-value building block in advanced organic synthesis. Its core value lies in its precise molecular architecture, which is critical for constructing complex pharmacophores and functional materials with targeted properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine atoms for modulating biological activity, metabolic stability, or material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets where fluorination is a common strategy.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance bioavailability and environmental persistence.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe Development: Employed to create fluorinated analogs of natural products or biochemical tools for studying enzyme mechanisms and protein-ligand interactions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel fluorination reactions and heterocycle synthesis.

Basic Information

Product Name	1H-Isoindol-1-One,4-Fluoro-2,3-Dihydro-(9Ci)
CAS No.	366452-96-2
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	4-Fluoro-2,3-dihydro-1H-isoindol-1-one; 4-Fluoro-1H-isoindole-1,3(2H)-dione (9CI); 4-Fluoro-2,3-dihydroisoindol-1-one; 4-Fluoro-1H-isoindole-1,3(2H)-dione; 4-Fluoro-1H-isoindolin-1-one; 4-Fluoro-2,3-dihydro-1H-isoindol-1-one (9CI); 4-Fluoro-1H-isoindole-1,3(2H)-dione (9CI); 4-Fluoro-1H-isoindolin-1,3-dione
EINECS	Contact for details

Quality Control

Our 1H-Isoindol-1-One,4-Fluoro-2,3-Dihydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.