Description

6-tert-Butyl 2-Methyl 5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-2,6-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and is valued for its structural complexity and role in modern medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Synthesis: Used in the production route for active pharmaceutical ingredients that feature the pyrrolopyrimidine core structure.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in analytical method development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	6-tert-Butyl 2-Methyl 5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-2,6-Dicarboxylate
CAS No.	365996-89-0
Molecular Formula	C15H19N3O4
Molecular Weight	305.33 g/mol
Synonyms	6-tert-Butyl 2-methyl 5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-2,6-dicarboxylate; 2,6-Pyrrolo[3,4-d]pyrimidinedicarboxylic acid, 5,7-dihydro-2-methyl-6-(1,1-dimethylethyl)-, 2,6-dimethyl ester; Methyl 6-(tert-butyl)-2-methyl-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-2,6-dicarboxylate; tert-Butyl methyl pyrrolopyrimidinedicarboxylate; Pyrrolopyrimidine dicarboxylate ester intermediate
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl 2-Methyl 5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-2,6-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.