Description

2-Cyano-5,7-Dihydro-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester is a high-value, heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions, CROs/CDMOs, and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting protein kinases for oncology and inflammatory diseases.
• Chemical Biology Probes: Used to create tool compounds for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Serves as a building block for developing new active ingredients with specific biological activity.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new chemical entities (NCEs) due to its versatile pyrrolopyrimidine scaffold.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Cyano-5,7-Dihydro-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	365996-88-9
Molecular Formula	C12H14N4O2
Molecular Weight	246.26 g/mol
Synonyms	tert-Butyl 2-cyano-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 6H-Pyrrolo[3,4-d]pyrimidine-6-carboxylic acid, 2-cyano-5,7-dihydro-, 1,1-dimethylethyl ester; 2-Cyano-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; BOC-Pyrrolopyrimidine derivative; Pyrrolo[3,4-d]pyrimidine tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates, supporting our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.