Description

tert-Butyl 2-(Methylsulfonyl)-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex small molecule therapeutics, particularly kinase inhibitors. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted small molecule drugs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology: Serves as a probe or tool compound for studying biological pathways and target validation.
• Custom Synthesis: A starting material for the preparation of more complex, functionalized pyrrolopyrimidine derivatives.

Basic Information

Product Name	tert-Butyl 2-(Methylsulfonyl)-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate
CAS No.	365996-87-8
Molecular Formula	C₁₂H₁₇N₃O₄S
Molecular Weight	299.35 g/mol
Synonyms	6-tert-Butoxycarbonyl-2-methylsulfonyl-5,7-dihydropyrrolo[3,4-d]pyrimidine; 2-(Methylsulfonyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic Acid tert-Butyl Ester; tert-Butyl 2-(Methylsulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 2-Methanesulfonyl-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic Acid tert-Butyl Ester; BOC-Protected 2-(Methylsulfonyl)pyrrolopyrimidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Methylsulfonyl)-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.