Description

3-(4-Trifluoromethylphenyl)Phenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenol group and a trifluoromethylphenyl moiety, makes it an essential intermediate for creating high-performance materials and active pharmaceutical ingredients. This compound is particularly valuable for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine atoms to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a core unit in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer & Resin Modifier: Incorporated into high-performance polymers and epoxy resins to impart enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for ligands in catalytic systems due to its reactive phenolic and aryl halide functionalities.
• Research & Development: An important reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-(4-Trifluoromethylphenyl)Phenol
CAS No.	365426-93-3
Molecular Formula	C13H9F3O
Molecular Weight	238.21 g/mol
Synonyms	[3-(4-Trifluoromethylphenyl)phenol]; 3-(4-(Trifluoromethyl)phenyl)phenol; 3-(α,α,α-Trifluoro-p-tolyl)phenol; 3-(p-Trifluoromethylphenyl)phenol; 1-Hydroxy-3-[4-(trifluoromethyl)phenyl]benzene; 3-(4-Trifluoromethylphenyl)phenol; Phenol, 3-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Trifluoromethylphenyl)Phenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.