Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(2-Thienyl)-,Propylester(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds containing fused pyrimidine and thiophene rings.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high-purity, structurally specific intermediates.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(2-Thienyl)-,Propylester(9Ci)
CAS No.	364620-13-3
Molecular Formula	C13H14N2O3S
Molecular Weight	278.33 g/mol
Synonyms	4-(Thiophen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid propyl ester; Propyl 4-(2-thienyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 1,2,3,4-Tetrahydro-6-methyl-2-oxo-4-(2-thienyl)-5-pyrimidinecarboxylic acid propyl ester; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2-thienyl)-, propyl ester; Tetrahydro-6-methyl-2-oxo-4-(2-thienyl)pyrimidine-5-carboxylic acid propyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.