Description

5-(Benzyloxymethyl)-6-Methyluracil is a specialized uracil derivative with a benzyl-protected hydroxymethyl group at the 5-position. This compound is a crucial synthetic intermediate in organic and medicinal chemistry, valued for its role in constructing nucleoside analogs and other heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside and nucleotide analogs with potential therapeutic activity.
• Antiviral Drug Research: Used in the research and development of compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor in the creation of chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme-substrate interactions, particularly with thymidylate synthase and other pyrimidine metabolism enzymes.
• Organic Synthesis: A versatile intermediate for introducing modified uracil moieties into more complex molecular architectures.
• Agrochemical Development: Potential use in the synthesis of novel pesticides or plant growth regulators based on heterocyclic chemistry.

Basic Information

Product Name	5-(Benzyloxymethyl)-6-Methyluracil
CAS No.	362690-43-5
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	6-Methyl-5-(benzyloxymethyl)uracil; 5-(Benzyloxymethyl)-6-methyl-1H-pyrimidine-2,4-dione; 6-Methyl-5-(phenylmethoxymethyl)-2,4(1H,3H)-pyrimidinedione; 5-(Benzyloxymethyl)-6-methylpyrimidine-2,4(1H,3H)-dione; 5-(Benzyloxymethyl)-6-methyl-2,4-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxymethyl)-6-Methyluracil is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be hygroscopic; handle and store under anhydrous conditions if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.