Description

6-Bromo-8-Cyclopentyl-5-Methyl-2-Methylsulfanyl-8H-Pyrido[2,3-D]Pyrimidin-7-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyridopyrimidinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and kinase inhibitor research. It is essential for medicinal chemistry R&D teams and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for drug discovery.
• Biochemical Tool Compound: Serves as a reference standard or a core scaffold for probing specific biological pathways and enzyme functions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	6-Bromo-8-Cyclopentyl-5-Methyl-2-Methylsulfanyl-8H-Pyrido[2,3-D]Pyrimidin-7-One
CAS No.	362656-25-5
Molecular Formula	C₁₄H₁₆BrN₃OS
Molecular Weight	354.26 g/mol
Synonyms	6-Bromo-8-cyclopentyl-5-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one; 8-Cyclopentyl-5-methyl-2-(methylthio)-6-bromo-8H-pyrido[2,3-d]pyrimidin-7-one; 362656-25-5; 6-Bromo-8-cyclopentyl-5-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7-one, 6-bromo-8-cyclopentyl-5-methyl-2-(methylthio)-; SCHEMBL23545427; BCPM 6-Br derivative
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Cyclopentyl-5-Methyl-2-Methylsulfanyl-8H-Pyrido[2,3-D]Pyrimidin-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.