Description

1-(4-Cyclopentylamino-2-Methylsulfanyl-Pyrimidin-5-Yl)-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine core structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and antiviral research domains.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing pyrimidine-based molecular frameworks.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and target validation studies.

Basic Information

Product Name	1-(4-Cyclopentylamino-2-Methylsulfanyl-Pyrimidin-5-Yl)-Ethanone
CAS No.	362656-11-9
Molecular Formula	C12H17N3OS
Molecular Weight	251.35 g/mol
Synonyms	5-Acetyl-4-(cyclopentylamino)-2-(methylthio)pyrimidine; Ethanone, 1-[4-(cyclopentylamino)-2-(methylthio)-5-pyrimidinyl]-; 4-(Cyclopentylamino)-2-(methylthio)-5-pyrimidinyl methyl ketone; 1-(4-(Cyclopentylamino)-2-(methylsulfanyl)pyrimidin-5-yl)ethan-1-one; 1-(4-Cyclopentylamino-2-methylsulfanyl-pyrimidin-5-yl)-ethanone; CAS 362656-11-9
EINECS	Contact for details

Quality Control

Our 1-(4-Cyclopentylamino-2-Methylsulfanyl-Pyrimidin-5-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.