Description

3-[2-Oxo-2-(4-Phenylpiperazin-1-Yl)Ethyl]Quinazolin-4(3H)-One is a sophisticated heterocyclic organic compound featuring a quinazolinone core linked to a phenylpiperazine moiety via a keto-ethyl bridge. This specific molecular architecture makes it a valuable pharmacological intermediate and a key building block in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly within the central nervous system and oncology research fields.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment for structure-activity relationship (SAR) studies and library synthesis.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and enzyme interactions related to its structural class.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecules in custom synthesis and process development.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	3-[2-Oxo-2-(4-Phenylpiperazin-1-Yl)Ethyl]Quinazolin-4(3H)-One
CAS No.	362494-42-6
Molecular Formula	C20H20N4O2
Molecular Weight	348.40 g/mol
Synonyms	3-[2-Oxo-2-(4-Phenyl-1-piperazinyl)ethyl]-4(3H)-quinazolinone; 1-(4-Oxo-3,4-dihydroquinazolin-3-yl)-2-(4-phenylpiperazin-1-yl)ethan-1-one; 3-[2-(4-Phenylpiperazin-1-yl)-2-oxoethyl]quinazolin-4(3H)-one; Quinazolin-4(3H)-one, 3-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-; 362494-42-6; UNII-8Z5J6Q2F4K; 8Z5J6Q2F4K
EINECS	Contact for details

Quality Control

Our production of 3-[2-Oxo-2-(4-Phenylpiperazin-1-Yl)Ethyl]Quinazolin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.