Description

5-(4-Methoxyphenyl)-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine is a high-value, heterocyclic organic compound featuring a triazolopyrimidine core, which serves as a critical building block in advanced chemical synthesis. Its molecular architecture, combining a methoxyphenyl group with a trifluoromethyl substituent, makes it a versatile intermediate for creating compounds with tailored electronic and steric properties. This product is essential for R&D and production teams in the pharmaceutical and agrochemical sectors seeking to develop new active ingredients.

Application

This specialized triazolopyrimidine derivative is primarily utilized as a key synthetic intermediate. Its applications are driven by its unique structural motifs, which are valuable in designing molecules with specific biological activities.

• Pharmaceutical Intermediate: Serves as a core scaffold in the research and development of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Acts as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	5-(4-Methoxyphenyl)-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine
CAS No.	361368-95-8
Molecular Formula	C₁₄H₉F₃N₄O
Molecular Weight	306.25 g/mol
Synonyms	5-(4-Methoxyphenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine; 7-(Trifluoromethyl)-5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidine, 5-(4-methoxyphenyl)-7-(trifluoromethyl)-; CAS 361368-95-8
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Methoxyphenyl)-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.