Description

4-(2,3-Dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and agrochemical sectors for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its dichlorophenyl and pyrimidine motifs for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and novel synthetic pathways.
• API Development: Integral to the process development and scale-up of potential Active Pharmaceutical Ingredients under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	4-(2,3-Dichlorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-5-Pyrimidinecarboxylic Acid
CAS No.	356566-53-5
Molecular Formula	C₁₂H₁₀Cl₂N₂O₃
Molecular Weight	301.13 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(2,3-dichlorophenyl)-; 4-(2,3-Dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxopyrimidine-5-carboxylic acid; 356566-53-5; 4-(2,3-Dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid; 2-Oxo-4-(2,3-dichlorophenyl)-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(2,3-Dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.