Description

5-((Z)-(5-Fluoro-2-Oxoindolin-3-Ylidene)Methyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid is a high-purity, non-natural indole derivative characterized by its specific isatin-pyrrole conjugate structure. This compound is of significant value as a key synthetic intermediate and a versatile scaffold in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel kinase inhibitors and targeted cancer therapeutics.
• Chemical Biology Probe: Used as a core scaffold in the development of fluorescent probes or activity-based protein profiling (ABPP) reagents due to its conjugated system.
• Agrochemical Research: Acts as a precursor in the development of new generation herbicides and plant growth regulators.
• Material Science: Investigated for use in organic electronic materials and as a ligand for metal-organic frameworks (MOFs) given its potential for coordination and π-π stacking.
• Academic Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-((Z)-(5-Fluoro-2-Oxoindolin-3-Ylidene)Methyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid
CAS No.	356068-93-4
Molecular Formula	C₁₇H₁₅FN₂O₃
Molecular Weight	314.31 g/mol
Synonyms	5-[(Z)-(5-Fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid; 5-[(5-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid; 5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid; 356068-93-4; Isatin-pyrrole conjugate; Fluorinated indole-pyrrole carboxylic acid.
EINECS	Contact for details

Quality Control

Our production of 5-((Z)-(5-Fluoro-2-Oxoindolin-3-Ylidene)Methyl)-2,4-Dimethyl-1H-Pyrrole-3-Carboxylic Acid adheres to strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.