Description

2-(2-Amino-5-Fluorophenyl)Acetohydrazide is a specialized aromatic hydrazide derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both a primary amine and a hydrazide group on a fluorinated phenyl ring, enabling its use in constructing complex heterocyclic and pharmaceutical scaffolds. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate fluorinated aromatic systems for enhanced activity.
• Heterocyclic Chemistry: Serves as a versatile starting material for the construction of pyrazole, triazole, oxadiazole, and other nitrogen-containing heterocycles via cyclization reactions.
• Chemical Biology & Proteomics: Can be utilized as a linker or a reactive handle in bioconjugation chemistry and the development of chemical probes.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers, dyes, and photoactive materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new synthetic routes.

Basic Information

Product Name	2-(2-Amino-5-Fluorophenyl)Acetohydrazide
CAS No.	356068-89-8
Molecular Formula	C8H10FN3O
Molecular Weight	183.18 g/mol
Synonyms	2-(2-Amino-5-fluorophenyl)acetohydrazide; 2-Amino-5-fluorophenylacetohydrazide; 5-Fluoro-2-hydrazinylmethylaniline; Acetic acid, (2-amino-5-fluorophenyl)-, hydrazide; 2-Amino-α-fluoro-5-phenylacetohydrazide; (2-Amino-5-fluorophenyl)acetic acid hydrazide; 356068-89-8; 2-(2-Amino-5-fluorophenyl)acetylhydrazine
EINECS	Contact for details

Quality Control

Our 2-(2-Amino-5-Fluorophenyl)Acetohydrazide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.