Description

1H-Cyclopentapyrimidine-1-Acetic Acid, 2-[[(4-Fluorophenyl)Methyl]Thio]-4,5,6,7-Tetrahydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutics. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, particularly for candidates in neurological and metabolic disease pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in various therapeutic areas.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes from laboratory to pilot and commercial scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing novel synthetic methodologies.

Basic Information

Product Name	1H-Cyclopentapyrimidine-1-Acetic Acid, 2-[[(4-Fluorophenyl)Methyl]Thio]-4,5,6,7-Tetrahydro-4-Oxo-
CAS No.	356058-42-9
Molecular Formula	C₁₇H₁₇FN₂O₃S
Molecular Weight	348.39 g/mol
Synonyms	2-[[(4-Fluorophenyl)methyl]thio]-4-oxo-4,5,6,7-tetrahydro-1H-cyclopentapyrimidine-1-acetic acid; 2-[(4-Fluorobenzyl)thio]-4-oxo-4,5,6,7-tetrahydro-1H-cyclopentapyrimidine-1-acetic Acid; 4,5,6,7-Tetrahydro-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1H-cyclopentapyrimidine-1-acetic Acid; CAS 356058-42-9; 1H-Cyclopentapyrimidine-1-acetic acid, 2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-; 356058-42-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.